Promethazine with Codeine Oral Alternative should be employed with caution in individuals with bone-marrow depression. Leukopenia and agranulocytosis are already documented, ordinarily when promethazine has been used in Affiliation with other identified marrow-harmful brokers.
Get clinical aid at once Should you have any really critical Uncomfortable side effects, such as: slow/shallow respiration, seizures.
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To safeguard younger kids from poisoning, generally lock basic safety caps and straight away spot the medication in a secure locale – one that is up and away and out of their sight and access.
Existence-threatening respiratory depression and Loss of life have transpired in youngsters who obtained codeine; most instances adopted tonsillectomy and/or adenoidectomy, and many of the children experienced proof of becoming an extremely-swift metabolizer of codeine on account of a CYP2D6 polymorphism. (five.3) Promethazine with Codeine Oral Solution is contraindicated in kids youthful than twelve several years of age As well as in youngsters young than eighteen yrs of age adhering to tonsillectomy and/or adenoidectomy.
We anticipate reposting the pictures the moment we've been able determine and filter out pictures that do not match the data supplied while in the drug labels. NDC Codes
In deciding to make use of a medicine, the threats of taking the medicine have to be weighed versus The nice it can do. This can be a choice you and your health care provider will make. For this medicine, the subsequent must be viewed as:
The diagnostic analysis of sufferers with this syndrome is sophisticated. In arriving at a prognosis, it's important to discover circumstances in which the clinical presentation includes both serious medical ailment (e.
Make sure you Adhere to the directions carefully, mainly because continuing constipation may result in a lot more critical complications.
The concomitant use of codeine with other identified sedatives, for instance Alcoholic beverages or benzodiazepines, can drastically enhance the chance of adverse And maybe unsafe results. Naloxone availability may help as a certain antidote to reverse considerable opioid overdose or CNS despair, even though they are secondary to concomitant use with other CNS depressing brokers.
While sure medicines really should not be utilised with each other in the least, in other conditions two various medicines can be employed together regardless of whether an interaction may possibly come about. In these circumstances, your health care provider may want to alter the dose, or other precautions may very well be important.
This medication may perhaps include sugar and/or Liquor. Warning is recommended When you have diabetic issues, Alcoholic beverages dependence, or Promethazine codeine syrup liver disease. Inquire your medical professional or pharmacist about applying this solution safely.
All healthcare gurus are strongly advised to finish the REMS education plan and recommend sufferers and their caregivers to the safe use and really serious challenges linked to opioids based upon these parameters.[thirty] Equally, the productive use of the Prescription Drug Monitoring Software (PDMP) can identify individuals who are probably at risk of building dependence and subsequent addiction to opioids.
The causal part of opioids while in the medical syndrome of hypogonadism is not known since the a variety of medical, physical, Life-style, and psychological stressors that could impact gonadal hormone amounts have not been sufficiently controlled for in research executed to this point [see ADVERSE REACTIONS (six)].